Selected Publications

Publications supported all or in part by the NDC award


*Voit RA, Hendel A, Pruett-Miller SM, Porteus MH. “Therapeutic gene editing and the generation of endogenous fluorescent reporters at the human globin loci.” Submitted to Nat. Methods (2012).

Xiong H, Lee RJ, Haura EB, Edwards JG, Dynan WS and Li S. “Intranuclear delivery of a novel antibody-derived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit.” Int. J. Radiat. Oncol. Biol. Phys. (2011). PMID: 22138455 PMC Journal – in press.

*Cao Z, Goyal D, Zhou Y, Meiler SE, Dynan WS. “Platforms for delivery of macromolecules to sites of DNA double-strand break repair.” Submitted (2012).

Dennis AM, Rhee WJ, Dublin SN, Sotto D and Bao G. “Quantum Dot-Fluorescent Protein FRET Probe for Monitoring Intracellular pH”, ACS Nano, 6: 2917-24 (2012). PMID: 22443420.

Tong S, Hou S, Ren B, Zheng Z and Bao G. “Self-assembly of Phospholipid-PEG Coating on Nanoparticles through Dual Solvent Exchange”, Nano Letters, 11: 3720-6 (2011). PMCID: PMC3173588.

Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA. “Microenvironmental Geometry Guides Platelet Adhesion and Spreading: a Quantitative Analysis at the Single Cell Level.” PLoS ONE, 6: e26437 (2011). PMCID: PMC3197646.

Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, Ware R, Fletcher DA, Lam WA. “In vitro models of microvascular occlusion and thrombosis using microfluidic technology.” J. Clinical Investigation, 122: 408–418 (2012). PMCID: PMC3248292.

Myers DR, Sakurai Y, Tsai M, Kita A, Lam WA. “Endothelialized microfluidics for studying microvascular interactions in hematologic diseases.” Journal of Visual Experiments, in press (2012). PMID: 22760254.


*Deriano L, Chaumeil J, Coussens M, Multani A, Chou YF, Alekseyenko AV, Chang S, Skok JA, Roth DB The RAG2 C-terminus suppresses genomic instability and lymphomagenesis. Nature. 471:119-23 (2011). PMCID: PMC3174233.

*Meiler SE, Wade M, Kutlar F, Yerigenahally SD, Xue Y, Moutouh-de Parseval LA, Corral LG, Swerdlow PS, Kutlar A. Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice. Blood. May 2, 2011. [Epub ahead of print]. PMCID: PMC3148160.

*Cao Z, Kuhne WW, Steeb J, Merkley MA, Zhou Y, Janata J and Dynan WS. Use of a microscope stagemounted Nickel-63 microirradiator for real-time observation of the DNA double-strand break response. Nucleic Acids Res. 38:e144 (2010). PMCID: PMC2919731.

Ha KS, Takeda Y and Dynan WS. Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells. DNA Repair, 10:252-259 (2011). PMCID: PMC3046316.

Cao Z, Goyal D, Zhou Y, Meiler SE and Dynan WS. A combination strategy for delivery of an engineered protein-based nanocomplex to sites of DNA double-strand break repair in living cells. Submitted (2011).

Xiong X, Lee RJ, Haura EB, Edwards JG, Dynan WS and Li S. Intranuclear delivery of a novel antibodyderived radiosensitizer targeting the DNA-dependent protein kinase catalytic subunit. Int J Radiat Oncol Biol Phys. 2012 July 1; 83(3): 1023-30. PMID: 22138455.

Smith AM and Nie SM. Bright and compact alloyed quantum dots with broadly tunable near-Infrared absorption and fluorescence spectra through mercury cation exchange. J. Am. Chem. Soc.,133:24-26. PMCID: PMC3102112.

Smith AM, Wen MM, Wang MD and Nie SM. Size-minimized quantum dots for molecular and cellular imaging. Nobel Symposium 138: Single Molecule Spectroscopy in Chemistry, Physics and Biosciences: Springer Series in Chemical Physics, Volume 96, Pages: 187-201 (2010). NIHMSID: NIHMS303746.

Smith AM, Wen MM and Nie SM. Imaging dynamic cellular events with quantum dots – the bright future. The Biochemist, 32:12-17 (2010). PMCID: PMC2932459.


Smith AM and Nie S. Semiconductor nanocrystals: structure, properties, and bandgap engineering. Acc. Chem. Res. 43, 190-200 (2010).

Li S, Nguyen L, Xiong H, Wang M, Hu TC, She JX, Serkiz SM, Wicks GG and Dynan WS. Porous-wall hollow glass microspheres as novel carriers for biomolecules. Nanomedicine, 6, 127-136 (2010).

Cao Z, Kuhne WW, Steeb J, Zhou Y, Janata J and Dynan WS. A microscope stage-mounted Nickel-63 microirradiation system for controlled induction of DNA double-strand break repair foci. Nucleic Acids Res. 2010 May 19 [Epub ahead of print].


Puthenveetil S, Liu DS, White KA, Thompson S and Ting AY. Yeast display evolution of a kinetically efficient 13-amino acid substrate for lipoic acid ligase. Journal of the American Chemical Society, 131, 16430-16438 (2009).

Xiong H, Li S, Yang Z, Burgess RR and Dynan WS. E. coli expression of soluble, active scFv variants containing a nuclear localization signal. Protein Expr Purif. 66, 172-180 (2009).

Li S, Kuhne WW, Kulharya A, Hudson F, Ha K, Dynan WS. Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance. Nucleic Acids Res. 37, 6746-6753 (2009).

Nitin N, LaConte L and Bao G. Tat Peptide Is Capable of Importing Large Nanoparticles across Nuclear Membrane. Ann Biomed Eng. 37, 2018-27 (2009).

Bao G, Rhee WJ, Tsourkas A. Fluorescent Probes for Live-Cell RNA Detection.  Annu Rev Biomed Eng. 11, 25-47 (2009).

Bao G, Santangelo P, Nitin N and Rhee WJ, Nanostructured Probes for In Vivo Gene Detection, in Vol. 5, Nanomedicine (Ed. Viola Vogel), pp. 143-165, Nanotechnology Series, WILEY-VCH, Weinheim, Germany, 2009.


Dynan W, Takeda Y, Roth D, Bao G. Understanding and re-engineering nucleoprotein machines to cure human disease. Nanomedicine (Lond.) 3:93-105 (2008)


Dynan WS, Takeda Y, Li S. Modifying the function of DNA repair nanomachines for therapeutic benefit. Nanomedicine 2:74-81 (2006).

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